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KMID : 1036920130180030148
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Annals of Pediatric Endocrinology & Metabolism
2013 Volume.18 No. 3 p.148 ~ p.151
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Insulin pump therapy in transient neonatal diabetes mellitus
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Park Joong-Heum
Kang Jeong-Hee
Lee Kyu-Hyung
Kim Nam-Hyo
Yoo Han-Wook
Lee Dae-Yeol
Yoo Eun-Gyong
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Abstract
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Neonatal diabetes mellitus (NDM) is a rare disease requiring insulin treatment. Its treatment is primarily focused on maintaining adequate glycemic control and avoiding hypoglycemia. Although insulin pump therapy is frequently administered to adults and children, there is no consensus on the use of insulin pumps in NDM. A 10 day-old female infant was referred to us with intrauterine growth retardation and poor weight gain. Hyperglycemia was noted, and continuous intravenous insulin infusion was initiated. However, the patient’s serum glucose levels fluctuated widely, and maintaining the intravenous route became difficult within the following weeks. Continuous subcutaneous insulin infusion with an insulin pump was introduced on the twenty-fifth day of life, and good glycemic control was achieved without any notable adverse effects including hypoglycemia. We suggest that the insulin pump is a safe and effective mode for treating NDM and its early adoption may shorten the length of hospital stays in patients with NDM.
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KEYWORD
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Diabetes mellitus, Newborn infant, Insulin infusion systems
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